This project focuses on an open-source microfluidic platform designed to study fibroblast migration and proliferation during wound healing. By simulating the pathological microenvironment of a diabetic wound, the device enables the creation of a controlled lesion to monitor and collect precise data on wound regeneration rates.
The proposal features a core geometry with modifications in channel architecture, length, and well size. These structural variations allow for systematic testing of how physical constraints and geometry influence cellular behavior and migration patterns.
Medical tags
- Clinical need
- Support to laboratory practice
- Area
- Cellular pathology
- Technology
- In vitro diagnostic device
- Project keywords
- Microfluidic Systems, iCells, Lab-on-a-chip, Comunidad de Madrid, diabetic, organ-on-a-chip, wound recovery
- Device classification
- I