Basic microfluidic system for studying the phenomenon of tumoral angiogenesis

Basic microfluidic system for studying the phenomenon of tumoral angiogenesis

Illustrative project image

Medical tags

Clinical need
Support to laboratory practice
Area
Cellular pathology
Technology
In vitro diagnostic device
Project keywords
iCELLS-CM, Lab-on-a-Chip, Organ-on-a-Chip, Microfluidic Systems, Comunidad de Madrid, Angiogenesis Tumoral, Additive Manufacturing

Project description

This proposal focuses on the development of a microfluidic system designed to replicate the biological conditions required for vascular angiogenesis. To achieve this, a multi-channel architecture will be implemented to establish a differential field of conditions, inducing cells to migrate between channels and sprout new blood vessels.

Success depends on the integration of hydrogels and chemical gradients, strategically placed to provide the precise stimuli necessary for cellular mobilization.